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Why Mathematics? | Statistical Significance and Practical Importance: Effect Size, Uncertainty and Decisions

Why is mathematics important when a result is “statistically significant” but may not matter in real life? Significance tests compare data with a null model, while effect sizes and confidence intervals describe magnitude and uncertainty. Good decisions need all three, plus costs, benefits and context.

Did You Know? A tiny effect can achieve a very small p-value in a huge sample, while an important effect can miss a conventional threshold in a small, noisy study.

Full chapter index

Chapters 1–7 · Understand the question
  1. The decision question
  2. The p-value definition
  3. An authoritative professional statement
  4. A worked comparison
  5. Calculate test statistics
  6. Interpret magnitude
  7. Confidence intervals
Chapters 8–14 · Reproduce the example
  1. Effect sizes
  2. Minimum important difference
  3. Failure to reject
  4. Multiple testing
  5. Researcher degrees of freedom
  6. Association versus causation
  7. Model assumptions
Chapters 15–21 · Check assumptions
  1. Sample size and p-values
  2. Equivalence and noninferiority
  3. Bayesian alternatives
  4. Decision analysis
  5. Diagnostics
  6. Validation plan
  7. Limits
Chapters 22–28 · Explore applications
  1. A spreadsheet workflow
  2. A coding workflow
  3. Applications and careers
  4. A student investigation
  5. Common misconceptions
  6. Connection to recent mathematics articles
  7. Guidance for students and parents
Chapters 29–34 · Study and verify
  1. Practice questions
  2. Frequently asked questions
  3. A reporting checklist
  4. The magnitude-precision plane
  5. Final significance audit
  6. Useful next reading

CHAPTER 1 OF 34 · Understand the question

1. The decision question

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A p-value addresses compatibility with a statistical model. It does not by itself answer whether an effect is large, valuable, causal or worth acting on.

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CHAPTER 2 OF 34 · Understand the question

2. The p-value definition

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Under a specified null model, the p-value is the probability of a test statistic at least as extreme as observed, not the probability that the null hypothesis is true.

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CHAPTER 3 OF 34 · Understand the question

3. An authoritative professional statement

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The American Statistical Association warns that scientific conclusions and decisions should not be based only on whether a p-value crosses a threshold. Read the ASA statement.

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CHAPTER 4 OF 34 · Understand the question

4. A worked comparison

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Study A estimates an improvement of 0.2 marks with SE=0.05. Study B estimates 4 marks with SE=2.5.

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CHAPTER 5 OF 34 · Understand the question

5. Calculate test statistics

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Against zero, z_A=0.2/0.05=4. Study B gives z_B=4/2.5=1.6.

StudyEstimateSEz
A0.20.054
B42.51.6
Magnitude and precision.

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CHAPTER 6 OF 34 · Understand the question

6. Interpret magnitude

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A is precisely different from zero but only 0.2 marks. B is much larger but uncertain. Whether either matters depends on educational and practical thresholds.

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CHAPTER 7 OF 34 · Understand the question

7. Confidence intervals

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Approximate 95% intervals are A: 0.102 to 0.298 and B: -0.9 to 8.9 marks. Intervals show magnitude ranges hidden by binary labels.

StudyLowerUpper
A0.1020.298
B-0.98.9
Approximate 95% intervals.

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CHAPTER 8 OF 34 · Reproduce the example

8. Effect sizes

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Report raw differences in meaningful units and, when useful, standardized effects. Standardisation aids comparison but can hide the original educational scale.

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CHAPTER 9 OF 34 · Reproduce the example

9. Minimum important difference

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Define a practical threshold before seeing results. An interval entirely above it supports a stronger usefulness claim than merely excluding zero.

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CHAPTER 10 OF 34 · Reproduce the example

10. Failure to reject

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A p-value above 0.05 does not prove no effect. It may reflect low power, noisy measurement or a wide range of compatible effects.

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CHAPTER 11 OF 34 · Reproduce the example

11. Multiple testing

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Testing many outcomes raises the chance of small p-values under null models. Pre-specification, adjustment and transparent reporting limit selective claims.

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CHAPTER 12 OF 34 · Reproduce the example

12. Researcher degrees of freedom

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Flexible exclusions, outcomes and models can change p-values. Sensitivity analyses and complete reporting show robustness.

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CHAPTER 13 OF 34 · Reproduce the example

13. Association versus causation

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A small p-value for an observational association does not establish causal identification. Design and assumptions matter.

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CHAPTER 14 OF 34 · Reproduce the example

14. Model assumptions

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Normality, independence, variance structure, randomisation and survey design affect the reference distribution and SE.

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CHAPTER 15 OF 34 · Check assumptions

15. Sample size and p-values

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For a fixed effect, larger n usually lowers SE and increases the test statistic. Significance can become almost inevitable for trivial nonzero differences.

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CHAPTER 16 OF 34 · Check assumptions

16. Equivalence and noninferiority

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When the goal is to show differences are acceptably small, equivalence-style hypotheses are more appropriate than failing to reject zero.

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CHAPTER 17 OF 34 · Check assumptions

17. Bayesian alternatives

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Posterior distributions can address probability statements under specified priors and likelihoods, but still require decisions about meaningful magnitude and loss.

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CHAPTER 18 OF 34 · Check assumptions

18. Decision analysis

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Combine estimated benefits, harms, costs, uncertainty and values. Statistical evidence supplies inputs; mathematics does not choose social priorities alone.

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CHAPTER 19 OF 34 · Check assumptions

19. Diagnostics

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Check pre-specified hypotheses, effect units, interval, practical threshold, power, multiple testing, design, assumptions and sensitivity.

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CHAPTER 20 OF 34 · Check assumptions

20. Validation plan

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Reproduce z=4 and 1.6, calculate both intervals, vary sample size, apply a practical threshold and simulate multiple testing.

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CHAPTER 21 OF 34 · Check assumptions

21. Limits

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No single p-value, effect size or interval resolves measurement bias, publication bias, confounding or decision values.

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CHAPTER 22 OF 34 · Explore applications

22. A spreadsheet workflow

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Store estimate, SE, test statistic, p-value, confidence interval, effect unit, practical threshold, multiplicity adjustment and decision consequence.

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CHAPTER 23 OF 34 · Explore applications

23. A coding workflow

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Reproduce test statistics, compute intervals, simulate power and multiplicity, and run sensitivity specifications without outcome-driven deletion.

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CHAPTER 24 OF 34 · Explore applications

24. Applications and careers

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Researchers, policymakers, engineers and education leaders interpret statistical evidence for decisions.

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CHAPTER 25 OF 34 · Explore applications

25. A student investigation

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Simulate the same tiny effect at several sample sizes, then compare p-values, intervals and practical-threshold decisions.

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CHAPTER 26 OF 34 · Explore applications

26. Common misconceptions

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p<0.05 is not proof, p>0.05 is not no effect, statistical significance is not practical importance, and association is not causation.

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CHAPTER 27 OF 34 · Explore applications

27. Connection to recent mathematics articles

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The confidence-interval guide shows compatible magnitudes. The sample-size guide explains power and precision inputs.

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CHAPTER 28 OF 34 · Explore applications

28. Guidance for students and parents

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Students should translate effects back into marks, minutes or probabilities. Parents can ask whether a school intervention changed outcomes by a meaningful amount, not only whether p<0.05.

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CHAPTER 29 OF 34 · Study and verify

29. Practice questions

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  • Calculate two z statistics.
  • Calculate both intervals.
  • Define a practical threshold.
  • Increase n.
  • Diagnose multiple testing.

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CHAPTER 30 OF 34 · Study and verify

30. Frequently asked questions

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### Is a p-value the probability the null is true? No.

### Does significance mean large effect? No.

### Does nonsignificance prove no effect? No.

### Should p-values be hidden? No; they should be interpreted with magnitude, uncertainty and design.

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CHAPTER 31 OF 34 · Study and verify

31. A reporting checklist

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Report hypothesis and model, estimate and units, SE, interval, p-value, practical threshold, sample and design, multiplicity, assumptions, sensitivity and decision context.

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CHAPTER 32 OF 34 · Study and verify

32. The magnitude-precision plane

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Evidence has at least two dimensions: how large the effect is and how precisely it is known. A binary threshold collapses both.

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CHAPTER 33 OF 34 · Study and verify

33. Final significance audit

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Confirm p-value meaning, effect units and interval, pre-specified importance threshold, power, multiplicity, causal design, assumption checks, sensitivity and no threshold-only decision.

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CHAPTER 34 OF 34 · Study and verify

34. Useful next reading

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Continue through the Mathematics Learning Hub. Recalculate one uncertainty measure and explain which decision it can and cannot support.

Contents · Previous chapter · Mathematics Learning Hub

Extended practice laboratory

Practice case 1: Define null

Setup: Start from the article’s significance-importance mechanism for case 1. Task: Change the named quantity, recompute the dependent result and compare with the original.

Check: Preserve the target population and sampling design, verify the uncertainty identity, state one diagnostic, record units and compare one defensible alternative with clear reasoning. Show the arithmetic, name the response and predictor units, and separate the numerical result from the claim it supports. Then vary one defensible assumption, calculate again and explain whether the conclusion changed because of the data, the fitted model or the validation purpose. Finish with one compact table or graph that could reveal a failure hidden by the summary.

Practice case 2: Set estimate A

Setup: Start from the article’s significance-importance mechanism for case 2. Task: Change the named quantity, recompute the dependent result and compare with the original.

Check: Preserve the target population and sampling design, verify the uncertainty identity, state one diagnostic, record units and compare one defensible alternative with clear reasoning. Show the arithmetic, name the response and predictor units, and separate the numerical result from the claim it supports. Then vary one defensible assumption, calculate again and explain whether the conclusion changed because of the data, the fitted model or the validation purpose. Finish with one compact table or graph that could reveal a failure hidden by the summary.

Practice case 3: Set SE A

Setup: Start from the article’s significance-importance mechanism for case 3. Task: Change the named quantity, recompute the dependent result and compare with the original.

Check: Preserve the target population and sampling design, verify the uncertainty identity, state one diagnostic, record units and compare one defensible alternative with clear reasoning. Show the arithmetic, name the response and predictor units, and separate the numerical result from the claim it supports. Then vary one defensible assumption, calculate again and explain whether the conclusion changed because of the data, the fitted model or the validation purpose. Finish with one compact table or graph that could reveal a failure hidden by the summary.

Practice case 4: Calculate z A

Setup: Start from the article’s significance-importance mechanism for case 4. Task: Change the named quantity, recompute the dependent result and compare with the original.

Check: Preserve the target population and sampling design, verify the uncertainty identity, state one diagnostic, record units and compare one defensible alternative with clear reasoning. Show the arithmetic, name the response and predictor units, and separate the numerical result from the claim it supports. Then vary one defensible assumption, calculate again and explain whether the conclusion changed because of the data, the fitted model or the validation purpose. Finish with one compact table or graph that could reveal a failure hidden by the summary.

Practice case 5: Set estimate B

Setup: Start from the article’s significance-importance mechanism for case 5. Task: Change the named quantity, recompute the dependent result and compare with the original.

Check: Preserve the target population and sampling design, verify the uncertainty identity, state one diagnostic, record units and compare one defensible alternative with clear reasoning. Show the arithmetic, name the response and predictor units, and separate the numerical result from the claim it supports. Then vary one defensible assumption, calculate again and explain whether the conclusion changed because of the data, the fitted model or the validation purpose. Finish with one compact table or graph that could reveal a failure hidden by the summary.

Practice case 6: Set SE B

Setup: Start from the article’s significance-importance mechanism for case 6. Task: Change the named quantity, recompute the dependent result and compare with the original.

Check: Preserve the target population and sampling design, verify the uncertainty identity, state one diagnostic, record units and compare one defensible alternative with clear reasoning. Show the arithmetic, name the response and predictor units, and separate the numerical result from the claim it supports. Then vary one defensible assumption, calculate again and explain whether the conclusion changed because of the data, the fitted model or the validation purpose. Finish with one compact table or graph that could reveal a failure hidden by the summary.

Practice case 7: Calculate z B

Setup: Start from the article’s significance-importance mechanism for case 7. Task: Change the named quantity, recompute the dependent result and compare with the original.

Check: Preserve the target population and sampling design, verify the uncertainty identity, state one diagnostic, record units and compare one defensible alternative with clear reasoning. Show the arithmetic, name the response and predictor units, and separate the numerical result from the claim it supports. Then vary one defensible assumption, calculate again and explain whether the conclusion changed because of the data, the fitted model or the validation purpose. Finish with one compact table or graph that could reveal a failure hidden by the summary.

Practice case 8: Calculate interval A

Setup: Start from the article’s significance-importance mechanism for case 8. Task: Change the named quantity, recompute the dependent result and compare with the original.

Check: Preserve the target population and sampling design, verify the uncertainty identity, state one diagnostic, record units and compare one defensible alternative with clear reasoning. Show the arithmetic, name the response and predictor units, and separate the numerical result from the claim it supports. Then vary one defensible assumption, calculate again and explain whether the conclusion changed because of the data, the fitted model or the validation purpose. Finish with one compact table or graph that could reveal a failure hidden by the summary.

Practice case 9: Calculate interval B

Setup: Start from the article’s significance-importance mechanism for case 9. Task: Change the named quantity, recompute the dependent result and compare with the original.

Check: Preserve the target population and sampling design, verify the uncertainty identity, state one diagnostic, record units and compare one defensible alternative with clear reasoning. Show the arithmetic, name the response and predictor units, and separate the numerical result from the claim it supports. Then vary one defensible assumption, calculate again and explain whether the conclusion changed because of the data, the fitted model or the validation purpose. Finish with one compact table or graph that could reveal a failure hidden by the summary.

Practice case 10: Define practical threshold

Setup: Start from the article’s significance-importance mechanism for case 10. Task: Change the named quantity, recompute the dependent result and compare with the original.

Check: Preserve the target population and sampling design, verify the uncertainty identity, state one diagnostic, record units and compare one defensible alternative with clear reasoning. Show the arithmetic, name the response and predictor units, and separate the numerical result from the claim it supports. Then vary one defensible assumption, calculate again and explain whether the conclusion changed because of the data, the fitted model or the validation purpose. Finish with one compact table or graph that could reveal a failure hidden by the summary.

Practice case 11: Increase n

Setup: Start from the article’s significance-importance mechanism for case 11. Task: Change the named quantity, recompute the dependent result and compare with the original.

Check: Preserve the target population and sampling design, verify the uncertainty identity, state one diagnostic, record units and compare one defensible alternative with clear reasoning. Show the arithmetic, name the response and predictor units, and separate the numerical result from the claim it supports. Then vary one defensible assumption, calculate again and explain whether the conclusion changed because of the data, the fitted model or the validation purpose. Finish with one compact table or graph that could reveal a failure hidden by the summary.

Practice case 12: Decrease n

Setup: Start from the article’s significance-importance mechanism for case 12. Task: Change the named quantity, recompute the dependent result and compare with the original.

Check: Preserve the target population and sampling design, verify the uncertainty identity, state one diagnostic, record units and compare one defensible alternative with clear reasoning. Show the arithmetic, name the response and predictor units, and separate the numerical result from the claim it supports. Then vary one defensible assumption, calculate again and explain whether the conclusion changed because of the data, the fitted model or the validation purpose. Finish with one compact table or graph that could reveal a failure hidden by the summary.

Practice case 13: Add multiple tests

Setup: Start from the article’s significance-importance mechanism for case 13. Task: Change the named quantity, recompute the dependent result and compare with the original.

Check: Preserve the target population and sampling design, verify the uncertainty identity, state one diagnostic, record units and compare one defensible alternative with clear reasoning. Show the arithmetic, name the response and predictor units, and separate the numerical result from the claim it supports. Then vary one defensible assumption, calculate again and explain whether the conclusion changed because of the data, the fitted model or the validation purpose. Finish with one compact table or graph that could reveal a failure hidden by the summary.

Practice case 14: Adjust multiplicity

Setup: Start from the article’s significance-importance mechanism for case 14. Task: Change the named quantity, recompute the dependent result and compare with the original.

Check: Preserve the target population and sampling design, verify the uncertainty identity, state one diagnostic, record units and compare one defensible alternative with clear reasoning. Show the arithmetic, name the response and predictor units, and separate the numerical result from the claim it supports. Then vary one defensible assumption, calculate again and explain whether the conclusion changed because of the data, the fitted model or the validation purpose. Finish with one compact table or graph that could reveal a failure hidden by the summary.

Practice case 15: Add confounding

Setup: Start from the article’s significance-importance mechanism for case 15. Task: Change the named quantity, recompute the dependent result and compare with the original.

Check: Preserve the target population and sampling design, verify the uncertainty identity, state one diagnostic, record units and compare one defensible alternative with clear reasoning. Show the arithmetic, name the response and predictor units, and separate the numerical result from the claim it supports. Then vary one defensible assumption, calculate again and explain whether the conclusion changed because of the data, the fitted model or the validation purpose. Finish with one compact table or graph that could reveal a failure hidden by the summary.

Practice case 16: Add randomisation

Setup: Start from the article’s significance-importance mechanism for case 16. Task: Change the named quantity, recompute the dependent result and compare with the original.

Check: Preserve the target population and sampling design, verify the uncertainty identity, state one diagnostic, record units and compare one defensible alternative with clear reasoning. Show the arithmetic, name the response and predictor units, and separate the numerical result from the claim it supports. Then vary one defensible assumption, calculate again and explain whether the conclusion changed because of the data, the fitted model or the validation purpose. Finish with one compact table or graph that could reveal a failure hidden by the summary.

Practice case 17: Test equivalence

Setup: Start from the article’s significance-importance mechanism for case 17. Task: Change the named quantity, recompute the dependent result and compare with the original.

Check: Preserve the target population and sampling design, verify the uncertainty identity, state one diagnostic, record units and compare one defensible alternative with clear reasoning. Show the arithmetic, name the response and predictor units, and separate the numerical result from the claim it supports. Then vary one defensible assumption, calculate again and explain whether the conclusion changed because of the data, the fitted model or the validation purpose. Finish with one compact table or graph that could reveal a failure hidden by the summary.

Practice case 18: Add Bayesian view

Setup: Start from the article’s significance-importance mechanism for case 18. Task: Change the named quantity, recompute the dependent result and compare with the original.

Check: Preserve the target population and sampling design, verify the uncertainty identity, state one diagnostic, record units and compare one defensible alternative with clear reasoning. Show the arithmetic, name the response and predictor units, and separate the numerical result from the claim it supports. Then vary one defensible assumption, calculate again and explain whether the conclusion changed because of the data, the fitted model or the validation purpose. Finish with one compact table or graph that could reveal a failure hidden by the summary.

Practice case 19: Add cost

Setup: Start from the article’s significance-importance mechanism for case 19. Task: Change the named quantity, recompute the dependent result and compare with the original.

Check: Preserve the target population and sampling design, verify the uncertainty identity, state one diagnostic, record units and compare one defensible alternative with clear reasoning. Show the arithmetic, name the response and predictor units, and separate the numerical result from the claim it supports. Then vary one defensible assumption, calculate again and explain whether the conclusion changed because of the data, the fitted model or the validation purpose. Finish with one compact table or graph that could reveal a failure hidden by the summary.

Practice case 20: Add harm

Setup: Start from the article’s significance-importance mechanism for case 20. Task: Change the named quantity, recompute the dependent result and compare with the original.

Check: Preserve the target population and sampling design, verify the uncertainty identity, state one diagnostic, record units and compare one defensible alternative with clear reasoning. Show the arithmetic, name the response and predictor units, and separate the numerical result from the claim it supports. Then vary one defensible assumption, calculate again and explain whether the conclusion changed because of the data, the fitted model or the validation purpose. Finish with one compact table or graph that could reveal a failure hidden by the summary.

Practice case 21: Audit p-value

Setup: Start from the article’s significance-importance mechanism for case 21. Task: Change the named quantity, recompute the dependent result and compare with the original.

Check: Preserve the target population and sampling design, verify the uncertainty identity, state one diagnostic, record units and compare one defensible alternative with clear reasoning. Show the arithmetic, name the response and predictor units, and separate the numerical result from the claim it supports. Then vary one defensible assumption, calculate again and explain whether the conclusion changed because of the data, the fitted model or the validation purpose. Finish with one compact table or graph that could reveal a failure hidden by the summary.

Practice case 22: Audit effect size

Setup: Start from the article’s significance-importance mechanism for case 22. Task: Change the named quantity, recompute the dependent result and compare with the original.

Check: Preserve the target population and sampling design, verify the uncertainty identity, state one diagnostic, record units and compare one defensible alternative with clear reasoning. Show the arithmetic, name the response and predictor units, and separate the numerical result from the claim it supports. Then vary one defensible assumption, calculate again and explain whether the conclusion changed because of the data, the fitted model or the validation purpose. Finish with one compact table or graph that could reveal a failure hidden by the summary.

Practice case 23: Audit interval

Setup: Start from the article’s significance-importance mechanism for case 23. Task: Change the named quantity, recompute the dependent result and compare with the original.

Check: Preserve the target population and sampling design, verify the uncertainty identity, state one diagnostic, record units and compare one defensible alternative with clear reasoning. Show the arithmetic, name the response and predictor units, and separate the numerical result from the claim it supports. Then vary one defensible assumption, calculate again and explain whether the conclusion changed because of the data, the fitted model or the validation purpose. Finish with one compact table or graph that could reveal a failure hidden by the summary.

Practice case 24: Name limits

Setup: Start from the article’s significance-importance mechanism for case 24. Task: Change the named quantity, recompute the dependent result and compare with the original.

Check: Preserve the target population and sampling design, verify the uncertainty identity, state one diagnostic, record units and compare one defensible alternative with clear reasoning. Show the arithmetic, name the response and predictor units, and separate the numerical result from the claim it supports. Then vary one defensible assumption, calculate again and explain whether the conclusion changed because of the data, the fitted model or the validation purpose. Finish with one compact table or graph that could reveal a failure hidden by the summary.

Practice case 25: Write conclusion

Setup: Start from the article’s significance-importance mechanism for case 25. Task: Change the named quantity, recompute the dependent result and compare with the original.

Check: Preserve the target population and sampling design, verify the uncertainty identity, state one diagnostic, record units and compare one defensible alternative with clear reasoning. Show the arithmetic, name the response and predictor units, and separate the numerical result from the claim it supports. Then vary one defensible assumption, calculate again and explain whether the conclusion changed because of the data, the fitted model or the validation purpose. Finish with one compact table or graph that could reveal a failure hidden by the summary.